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Old 08-02-2008, 01:25 PM   1 links from elsewhere to this Post. Click to view. #1 (permalink)
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Default 5-methyl-7-methoxy-isoflavone

Couple of my friends have used this supplement and got good gains.

What are your views on it guys?
Effective?
Side effects?

Rob
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Old 08-02-2008, 01:53 PM   #2 (permalink)
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Default Re: 5-methyl-7-methoxy-isoflavone

if its what i think it is(do maximuscle do an expensive sublingual version)i got nothing from it.
stuff i tried was absolutely foul!

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Old 08-02-2008, 02:15 PM   #3 (permalink)
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Default Re: 5-methyl-7-methoxy-isoflavone

Quote:
Originally Posted by crazycal1 View Post
if its what i think it is(do maximuscle do an expensive sublingual version)i got nothing from it.
stuff i tried was absolutely foul!
This isn't the best study in the world, but it backs up what Cal was saying...

Quote:
Nutr Cancer. 2007;59(2):163-8.

A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer.

Kumar NB, Krischer JP, Allen K, Riccardi D, Besterman-Dahan K, Salup R, Kang L, Xu P, Pow-Sang J.

Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA. kumar@moffitt.usf.edu

Our purpose was to evaluate the safety and effectiveness of purified isoflavones in producing an increase in plasma isoflavones and a corresponding change in serum sex hormone binding globulin (SHBG) and steroid hormone levels in men diagnosed with early stage prostate cancer. In this Phase II randomized, double-blinded, placebo-controlled trial, 53 prostate cancer patients with a Gleason score of 6 or below were supplemented with 80 mg purified isoflavones or placebo for 12 weeks. Changes in plasma isoflavones, serum steroid hormones, and safety markers were analyzed from baseline to 12 wk. A total of 50 subjects completed the study. Although significant increases in plasma isoflavones (P < 0.001) was observed with no clinical toxicity, the corresponding modulation of serum SHBG, total estradiol, and testosterone in the isoflavone-treated group compared to men receiving placebo was nonsignificant. Increasing plasma isoflavones failed to produce a corresponding modulation of serum steroid hormone levels in men with localized prostate cancer. The study establishes the need to explore other potential mechanisms by which prolonged and consistent purified isoflavone consumption may modulate prostate cancer risk.
PMID: 18001210 [PubMed - in process]
Anecdotal evidence on the boards say you might gains 4lbs from it...
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