LeeB

shouldnt matter too much.. theres people on here who have more knowledge of this than me so i may be corrected...

but in my opinion you should be concerened more with acheiveing consistent blood levels of the hormones... so if your having one tab a day... half it and have half at say 6am and then half at 6pm... your then having 25mg every 12 hours.. doing this exactly the same every day means your blood levels are always stable!